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OJVRTM

Online Journal of Veterinary Research©

 

Volume 19(3): 155-161, 2015


Malignant adenomyo-epithelioma in a feline mammary gland

 

De Campos CB1,2 DVM Ms, Gamba CO2 DVM Ms, Damasceno KA2 DVM Ms, Lavalle GE3 PhD, Cassali GD2 DVM Ms PhD

 

1Veterinary Clinic and Surgery, School of Agricultural and Veterinary Sciences, Sao Paulo State University, 2Department(s) of General Pathology, Biological Science Institute, 3Veterinary Clinic and Surgery, Federal University of Minas Gerais, Belo Horizonte,  Brazil.

 

ABSTRACT

 

De Campos CB, Gamba CO, Damasceno KA, Lavalle GE, Cassali GD., Malignant adenomyo-epithelioma in a feline mammary gland, Onl J Vet Res., 19(3): 155-161, 2015. Mammary neoplasms are the third most frequent tumor in felines. We describe  clinical, histopathological, and immuno-histochemical findings from a malignant adenomyo-epithelioma (MA) from a domestic queen. The cat presented with mammary masses and underwent radical unilateral mastectomy followed by chemotherapy. The tumor recurred and the animal survived 125 days but then died. Microscopy revealed a highly cellular malignant myoepithelial solid cell proliferation pattern with moderate pleomorphism and malignant epithelial proliferation in a tubular and papillary arrangement. The myoepithelial nature of the neoplastic cells was confirmed by p63 target antigen clone test.  Histo-pathological and immun0-histochemical results together with histological similarity between women and feline tumors suggested a diagnosis of MA.

 

Key-Words: feline, mammary gland, neoplasm, malignant adenomyoepithelioma.


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