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OJVRTM
Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Established 1994
ISSN 1328-925X
Volume 26 (12): 861-865, 2022.
Effect of Alhagi camelorum, Ziziphus
spinachristi and Levisticum officinalis supplements
on
blood glucose in male non-diabetic and diabetic Wistar
rats.
Mohammadi Abbass1, Emadi
ladan2, Barghi Maryam2
1Kerman
University of Medical Sciences, 2School
of Veterinary Medicine, University of
Kerman, Iran
ABSTRACT
Abbass MN, Ladan E, Maryam B., Effect of Alhagi camelorum, Ziziphus spinachristi and Levisticum officinalis supplements on blood glucose in male
non-diabetic and
diabetic Wistar rats, Onl J
Vet Res., 26 (12): 861-865, 2022. Authors describe effect of
methanolic extracts of alhagi camelorum, ziziphus spinachristi and levisticum officinal on blood glucose in normal and streptozotocin
diabetic male Wistar rats. Rats were fasted 15h prior
to experiments and 1ml of herbal extracts gavaged by
stomach tube. Blood glucose was determined by glucometer at 0, 30, 60 and
120min after treatments. Diabetes was induced by 60mg/kg Streptozotocin.
Then 5 groups of 6 non-diabetic and 6 diabetic rats each were gavaged 2g/kg maltose and 50mg/kg acarbose
(1), with 1000mg/kg alhagiacamelorum (2), Ziziphusspina Christi (3) and Levisticum officinal
(4) Controls were gavaged only 2g/kg maltose
(5). Compared with controls, Levisticum officinal
gavage had no effect on glucose in non-diabetic rats whereas Alhagiaca melorum and Ziziphus spina reduced it ~16-23% (P < 0.05).
In diabetic rats, these extracts reduced glucose ~14-21%. Our results suggest
that these plants extracts could ameliorate rises in blood sugar in diabetic
rats.
Keywords: Diabetes mellitus, Alpha
glucosidase, Alhagia camelorum, Ziziphus spina, levisticum officinal, rats.
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