MAIN


©1996-2018. All Rights Reserved. Online Journal of Veterinary Research . You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors. This journal satisfies the refereeing requirements (DEST) for the Higher Education Research Data Collection (Australia). Linking:To link to this page or any pages linking to this page you must link directly to this page only here rather than put up your own page.


OJVRTM

 Online Journal of Veterinary Research©

Volume 18(3): 213-230, 2014. Redacted 2017.


Modified double antibiotic synergy test.

 

Navid Ziaei-Darounkalaei1, Mehrdad Ameri2, Taghi Zahraei-Salehi3, Omid Ziaei-Darounkalaei4, Tahereh Mohajer-Tabrizi5 and Lotfollah Bornaei6

 

1Department of Veterinary Medicine, Faculty of Agriculture, Islamic Azad University, Yasuj Branch, 2Department of Pathology, Amgen Inc., USA- mameri@amgen.com,3Department of Microbiology, Faculty of Veterinary Medicine, University of Tehran,4Department of Orthopedic Surgery, Tehran University of Medical Sciences, 5Department of General Surgery, Gorgan University of Medical Sciences, Gorgan, 6Department of Animal Science, Faculty of Agriculture, Islamic Azad University, Yasuj Branch, Yasuj, Iran.

 

ABSTRACT

 

 

Ziaei-Darounkalaei N, Ameri M,  Zahraei-Salehi T,  Ziaei-Darounkalaei O, Mohajer-Tabrizi T, Bornaei L., Modified double antibiotic synergy test, Onl J Vet Res., 18(3): 213-230, 2014. Concurrent use of two or more antimicrobials is common in patients with complicated infectious disease. A double antibiotic synergy test for assessing the extent of synergistic or antagonistic effects of antimicrobial drugs on the growth inhibition of Staphylococcus aureus and Escherichia coli is described. Performance of the method was evaluated by testing 8 repeats of synergistic and antagonistic combinations of penicillin and gentamicin and erythromycin and clindamycin against Staphylococcus aureus and Escherichia coli compared with the traditional disk approximation technique. Based on average growth inhibition zones, combination of penicillin G and gentamicin showed greater inhibition compared with each individual antibiotic whereas a combination of erythromycin and clindamycin had less inhibition. Results suggest that the method identified combined antibiotic activity more efficiently than the traditional disk method.

 

Keywords, Antibiotic Inhibition test.


 

MAIN

 

FULL-TEXT (SUBSCRIPTION OR PURCHASE TITLE $25USD)