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OJVRTM
Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Established 1994
ISSN 1328-925X
27 (1): 10-17, 2023.
Effect
of Astragalus
polysaccharide on
erythrocyte-complement receptor type I adherence in chickens with infectious
bursal virus
Li Hongquan
College
of Veterinary Medicine and Animal Science, Shanxi Agricultural University,Taigu, Shanxi
030801,P.R. China. School of Veterinary Science, The
University of Queensland, Brisbane, QLD 4072, Australia）
ABSTRACT
Hongquan L., Effect of Astragalus polysaccharide on erythrocyte-complement
receptor type I adherence in chickens with infectious bursal virus, Onl J Vet Res., 27 (1): 10-17, 2023. Day old SPF Leghorn
chicks free of infectious bursal disease virus (IBDV) were inoculated 0.3 ml
IBDV at 26d and injected 5mg and 10mg/kg intramuscular Astralagus polysaccharide (APS)
twice daily from 26 to 31d. Compared with IBVD controls, in birds injected 5 or
10mg/kg, morbidity declined 42 and 58%
and mortality 14 and 18% (P < 0.05), respectively. Erythrocyte-C3b receptor
and erythrocyte-C3b immune complex rosettes rates in IBVD controls fell 65%
whereas in birds given 5 or 10mg/kg declined 44 and 22% remaining 56 and 34%
higher (P < 0.05) than IBVD controls.
Results suggest that APS may prevent erythrocyte immune complexes due to IBVD.
Keywords:
Astragalus
polysaccharides; Chicken; IBDV; Erythrocyte; immune adherence.
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