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OJVRTM
Online Journal of
Veterinary Research©
(Including Medical and Laboratory Research)
Established 1994
ISSN 1328-925X
Volume
28(4): 237-243, 2024.
Effect
of single impact load on equine articular cartilage.
Bowe
EA., Henson FMD, Caddick J,
Jeffcott LB, Davies ME.
Department
of Clinical Veterinary Medicine, University of Cambridge, Madingley
Road, Cambridge CB3OES
ABSTRACT
Bowe EA., Henson FMD, Caddick J, Jeffcott LB, Davies ME., Effect of single impact
load on equine articular cartilage, Onl J Vet Res., 28(4): 237-243,
2024. We report damage caused to equine articular
cartilage by a single impact load height of 10cm compared to 2.5cm. Samples of
control discs (no load) were compared with loaded discs and loads of 0.175J impacted at
0.7m/s when 500g was dropped from 2.5cm and 0.49J at 1.4m/s dropped from 10cm
equivalent to 8MPa and 38MPa respectively. A total of 45 unimpacted
discs, 45 discs impacted at 2.5 cm and 45 discs of cartilage impacted at 10cm
were analysed. Cartilages were processed for microscopy stained by Haematoxylin
& Eosin and Toluidine blue to visualize damage and determine proteoglycan from
extracellular matrix. We measured loss
of articular surface and proteoglycan content, which were more marked at 10cm than
2.5cm. The damage caused by a single impact load from a height of 2.5cm was
comparable to that previously reported in exercised horses and in clinical
cases of degenerative joint disease.
Key Words:
Equine, cartilage, load, osteoarthritis.
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