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OJVRTM

Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume  29 (10): 606-611, 2025.


 Caprine chromosomal DNA of Corynebacterium pseudotuberculosis,

 

Mohan P, Jayaprakasan V, Punnoose KT, Mini A.  

 

Project Directorate on Animal Disease Monitoring And Surveillance,  Hebbal, Bangalore – and Department of Microbiology, College of Veterinary and Animal Sciences, Kerala Agricultural University,  India

 

SUMMARY

 

Mohan P, Jayaprakasan V, Punnoose KT, Mini A.. Chromosomal DNA of goat Corynebacterium pseudotuberculosis, Onl J Vet Res., 29 (10): 606-611, 2025. Corynebacterium pseudotuberculosis from goat caseous lymphadenitis samples were evaluated against standard reference strains by biochemical and restriction endonuclease analysis (REA) of chromosomal DNA.   The enzymes Eco R1, Bgl II, Pst1 and Bam H1 were used to characterize the organisms Both bacteria were similar except for one isolate which fermented lactose. REA of both organisms yielded different restriction patterns digested with Pst I but not with Eco RI, Bam HI or Bgl II. Both strains were nitrate negative. A 3.2-Kb fragment was absent in 4 enzymes whereas 6.6-Kb and 3.6-Kb DNA fragments were found in both strains. The results suggest a high degree of homogeneity between field isolates and reference strains of C. pseudotuberculosis (goat).

 

Key words: Corynebacterium pseudotuberculosis, lymphadenitis - caprine - restriction endonuclease analysis.


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