Volume 23 (6):516-521, 2019.
Effect of Cucurbita maxima
seed extract on In vitro viability of
eggs, larvae and worms of Haemonchus contortus.
Ahmed N Abed Salih and Ali H Saliem
College of Veterinary Medicine,
University of Baghdad, Iraq
ABSTRACT
Abed Salih AN, Saliem AH., Effect of Cucurbita
maxima seed extract on In vitro viability
of eggs, larvae and worms of Haemonchus contortus, Onl J Vet Res., 23 (6):516-521, 2019. We
report dose dependent activity of Cucurbita maxima seed extract on in
Vitro survival of Haemonchus contortus eggs,
larvae and adult worms at doses of 50, 100 and 200mg/ml. Results were compared
against non-treated water controls and 25mg/ml Albendazole.
CM had no effect at 50mg/ml. At 100mg/ml egg hatching was inhibited ~19% and
larvae ~9% but CM had no effect on adult worms. With 200mg/ml hatching, larvae
and worms were inhibited 30.6, 15.9 and 7.7%. For albendazole
the same values were ~95, 87 and 80%. We find that Cucurbita maxima seed
extract had good dose-concentration correlation but poor effect against all
stages of Haemonchus contortus
in vitro compared with a standard
anti-helminth.
Key
words: Cucurbita maxima, gastrointestinal
worms, anti-helminthes. Raw data provided after references.
FULL-TEXT (SUBSCRIBE OR PURCHASE
TITLE)