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OJVR
Online
Journal of Veterinary Research©
Volume 13 (2):56-63, 2009. Redacted 2017.
Biofilm-forming
ability and antimicrobial resistance in Staphylococcus
intermedius isolated from dog-to-dog bite wounds.
CIISA
/ Faculdade de Medicina Veterinária da Universidade Técnica de Lisboa, Avenida
da Universidade Técnica, 1300-477 Lisboa, Portugal *Correspondence
ABSTRACT
Oliveira M, Mouro S, Niza
M, Lobo Vilela
C., Biofilm-forming ability and
antimicrobial resistance in Staphylococcus intermedius isolated from dog-to-dog
bite wounds, Onl J Vet Res., 13 (2):56-63, 2009. Staphylococci are commonly found in infected wounds,
although their virulence may differ among the strains. One of the relevant
virulence factors identified in staphylococci is biofilm, which allows for
evasion of host defences and survival at high antimicrobial concentrations.
Biofilm formation by Staphylococcus
intermedius isolates from infected and non-infected dog-to-dog bite wounds
was evaluated using a Fluorescent In Situ
Hybridisation (FISH) protocol. Seven isolates (43.75%) were able to form biofilm in vitro. Although no association was
found between wound infection and biofilm formation by S. intermedius (Friedman’s Test), biofilm production may influence
the outcome of an infection, by impairing antibiotics. We found that biofilm production was related with
resistance to most antimicrobials (Friedman’s Test), with the exception of
β-lactams AMP, P and PRL and the lincosamide DA.
Further studies
are required to determine whether biofilm-producing ability of S. intermedius is a significant
virulence trait for skin infections in dogs, and its potential zoonotic role.
Keywords: antimicrobial resistance;
biofilm; dog-to-dog bite wound; Staphylococcus intermedius; wound infection.
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