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OJVRTM
Online Journal of
Veterinary Research©
Volume 11 (1): 54-74, 2007. Extensively redacted 2018.
Effect of Vitamin C on cadmium toxicity in Tilapia (Oreochromis
niloticus).
Abbas HHH1,
Hammada MM2, Miller JD.
1 Hydrobiology Department, Veterinary Research
Division, National Research Center, El-Bohooth St. Dokki, Giza, 2 3American University in Cairo, Tahrer Square, Cairo, Egypt.
ABSTRACT
Abbas HHH, Hammada MM, Miller JD., Effect of Vitamin C on cadmium
toxicity in Tilapia (Oreochromis niloticus),
Onl J Vet Res., 11 (1):54-74, 2007. We report effect of Vitamin C on
acute cadmium (Cd) toxicity in freshwater Nile Tilapia. Groups of 70 Nile Tilapia each, were exposed to
1/10 LC50 Cd, 1/10 LC50 Cd + 500mg/L vitamin C, or 1/10
LC50 Cd + 1000mg/L vitamin C. Controls (n =70) were fish with
undetectable cadmium and no treatment. At 50 days fish were sacrificed for plasma enzymes and tissue microscopy.
Fish exposed to cadmium only, revealed abnormal blood constituents and
bioaccumulation in vital organs, with reduced growth, meat quality and blood
physiology of Nile tilapia. However, fish exposed to the same concentration of
cadmium supplemented with vitamin C showed significant differences in the
values of growth rates, meat quality and other physiological and biochemical
parameters compared with controls. Histological examination revealed damage to
gills and liver of fishes exposed to cadmium. In comparison, the histological
sections of the same organs of fish supplemented with vitamin C showed that
these organs were normal.
Key words: Toxicology,
Vitamin C, Nile tilapia, Physiology, Histopathology.
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