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OJVRTM
Online
Journal of Veterinary Research ©
15 (1): 22-30, 2011. Extensively
redacted 2017.
Effect of flunixin meglumine on pregnancy
rate in heat stressed Holstein dairy cows
Behrang Ekrami (DVM, PhD) 1,
*; Hamid Ghasemzadeh-Nava (DVM, PhD) 2;
Parviz Tajik (DVM, PhD) 2; Mahmood Bolourchi (DVM, PhD) 2; Amin Tamadon
(DVM, PhD) 3
1- Department of Clinical Sciences, Faculty of Veterinary
Medicine, Science and Research Branch, Islamic Azad University,
2- Department of Clinical Sciences,
Faculty of Veterinary Medicine, University of Tehran, Tehran, 3- Department of
Animal Health Management, School of Veterinary Medicine, Shiraz University
& Stem Cell and Transgenic Technology Research Center, Shiraz University of
Medical Sciences Shiraz, Iran.
ABSTRACT
Ekrami B, Ghasemzadeh-Nava H, Tajik P, Bolourchi
M, Tamadon A., Effect of flunixin
meglumine on pregnancy rate in heat stressed Holstein
dairy cows, Onl J Vet Res, 15 (1): 22-30,
2011. The effect of flunixin
meglumine injection after artificial insemination on pregnancy rate in
heat stressed dairy cows is described. Treatment was done with dominant
follicle and/or functional corpus luteum.
Cows were subjected to timed artificial insemination based on Select-OvSynch with 100-µg IM gonadotropin releasing hormone 7
days before and 48 hours after 25-mg IM PGF2α. Cows received
one timed artificial insemination with frozen thawed proved semen 16 to 22
hours after the second gonadotropin releasing hormone injection.
Groups of 40 cows each, were injected 1.1 mg/kg flunixin meglumine IM 2 to 5 post
insemination daily, a same dose of flunixin meglumine but at 10 to 13 days, and controls not
given drug. Plasma progesterone or presence of CL
were not different compared with controls. We found no significance difference between those given flunixin meglumine at 10-13 days
(20%) or 2-5 days or control (15%). Flunixin meglumine administration did not increase
pregnancy.
Keywords: Flunixin meglumine, Heat stress,
Pregnancy, Holstein dairy cow
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