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OJVRTM
Online Journal of Veterinary Research©
Volume 17 (5): 270-279, 2013. Extensively Redacted 2017.


Effects of dietary garlic powder supplementation on circulating biochemical and oxidant/antioxidant profile in male Wistar rats.

 

Vahide Ghodsi, Hasan Baghshani*

 

Department of Basic Sciences, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

 

ABSTRACT

 

Ghodsi V, Baghshani H., Effects of dietary garlic powder supplementation on circulating biochemical and oxidant/antioxidant profile in rats, Onl J Vet Res., 17 (5): 270-279, 2013. Effect of a 42 day, 5% dietary garlic supplement on rat (6) blood oxidative stress biomarkers and biochemistry is reported. Results were compared with 6 control rats not given supplement. The supplement had no effect on glucose, cholesterol, total protein, albumin, creatinine, urea, uric acid, total bilirubin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, lactate dehydrogenase, superoxide dismutase,  glutathione peroxidase,  malondialdehyde or protein carbonyl levels. However ferric reducing ability of plasma (FRAP) and glutathione (GSH) increased and triglyceride concentrations were reduced.  Five percent dietary garlic powder supplementation in rats may have some effect on non-enzymatic antioxidant status but does not appear to induce adverse effects.

 

Keywords: garlic, oxidant/antioxidant parameters, plasma biochemistry


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