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OJVRTM
Online
Journal of Veterinary Research©
(Including Medical and
Laboratory Research)
Established 1994
ISSN 1328-925X
Volume 29 (10):
593-598, 2025.
Effect of influenza A immunogenic glycoprotein on antibody in
hens.
Bogoyavlenskiy AP, Berezin VE, Tolmacheva VP, Khudyakova SS, Ogneva AV
Laboratory of Antivirus Protection, Institute of
Microbiology & Virology, Almaty, Kazakhstan,
ABSTRACT
Bogoyavlenskiy
AP, Berezin VE, Tolmacheva
VP, Khudyakova SS, Ogneva
AV Effect of influenza A
immunogenic glycoprotein on antibody in hens, Onl J Vet Res., 29 (10): 593-598, 2025. Immunogenicity of influenza
A subunit in glycoprotein micelle glycoside Quil A
and Freund's adjuvant were compared with formalinized whole virus. The results
showed that immunization of the influenza antigen preparations induced variable
levels of antibodies at 14, 21, 35, 77, 98 and 300 days postimmunization.
Immune Stimulating complexes (ISCOMs) were the most efficient antigen
formulation of purified FPV glycoproteins stimulating a higher level of humoral
immunity than whole virus or glycoprotein micelles. ISCOMs also stimulated a
high level of antibodies in egg-yolk.
Egg-yolk antibody titers were correlated with the
level of serum antibodies.
Key
words: Humoral, Immunity, Influenza, Vaccines, ISCOMs, Chickens.
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