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OJVRTM

Online Journal of Veterinary Research©

 (Including Medical and Laboratory Research)

Established 1994
ISSN 1328-925X

 

 Volume 25 (9):672-676, 2021.

Effect of acute intravenous haloperidol on hematology in pigeons (Columba livia domestica).

 

Moosa Javdani1, Zahra Nikousefat1, Mohammad Hashemnia2, Ali Jalili1

 

Department of 1Clinical Sciences and 2Pathobiology, Veterinary Medicine Faculty, Razi University, Kermanshah, Iran

 

ABSTRACT

 

Javdani M, Nikousefat Z, Hashemnia M, Jalili A., Effect of acute intravenous haloperidol on hematology in pigeons (Columba livia domestica), Onl J Vet Res., 25 (9):672-676, 2021. We report effect of a short-acting neuroleptic haloperidol on hematological and biochemical changes in naïve racing pigeons (Columba livia domestica). Groups of 20 pigeons each were injected 4 mg/kg haloperidol and blood sampled at 15 and 90 minutes. For controls (n=20) blood was taken before injections. For hematology, blood was taken from ulnar veins into EDTA vacutainers whereas for biochemical values was collected into tubes for serum. Total erythrocyte and leukocytes, hemoglobin (Hb), packed cell volume (PCV), differential leukocytes, serum protein (TP), albumin and cortisol (CoE) were measured. Our results show slight rise at 15min in RBC and PCV but declines of ~6% after 90min injection. Other changes in hematology were very small and not significant. However, we did find large increases 53-60% in serum cortisol even only after 15 min and heterophil/leucocyte ratio (40-54%) over the 15-90 minute period. Our results followed a biphasic pattern in captured birds as reported by others. Our results suggest that haloperidol may reduce capture induced stress in pigeons.

 

Key words: pigeons, haloperidol, hematological and biochemical parameters. Raw data provided.

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