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OJVRTM
Online Journal of
Veterinary Research©
Volume 10 (2) : 177 - 201, 2006. Extensively redacted 2018.
Clinical significance of Helicobacter infection in gastric mucosa of cats
Akhtardanesh B1, Mohammadi M2, Jamshidi S3,
Sassani F3, Bokaie S3
1Small
animal internal medicine Department, Veterinary faculty, Shahid Bahanar University, Kerman 2Biotechnology
Research Center, Pasteur Institute of Iran 3Veterinary faculty, Tehran
University
ABSTRACT
Akhtardanesh B, Mohammadi M, Jamshidi S,
Sassani F, Bokaie S., Clinical significance of Helicobacter
infection in gastric mucosa
of cats, Onl J Vet Res., 10 (2) 177-210, 2006. The presence of spiral bacteria in the stomach of cats has been documented. However
its zoonotic potential, clinical significance and
prevalence are still poorly documented. We report prevalence of Helicobacter and gastritis in the
stomach of 27 pet and 30 stray cats and diagnostic
tools for its detection. The cats from different locations were isolated and
their gastric samples underwent cytology, rapid urease test, histopathology and
genus/species specific PCRs. According to 16srRNA PCR assay, total prevalence of Helicobacter infection was 100% in domestic cats and 56.7% in
strays. Cats were frequently colonized by Candidatus
H. heilmannii and H. felis with no direct association to
existing chronic gastritis or gastric lesions. There
was no significant difference between the presence of erosion and ulcer in two
groups but advertence to McNemar test determined that
the prevalence of erosion was significantly higher in the antrum (p<0.05). Infected animals generally demonstrated a
local immune response characterized by lymphoid follicular hyperplasia.
Interestingly, the rate of Helicobacter
infection especially for Candidatus H. heilmannii was
significantly higher in pet cats (81%) compared with strays (43.3%) suggesting
that living conditions may play an etiologic role in prevalence.
Key words: Chronic gastritis, H. heilmannii, H.
felis, H. pylori, cat
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