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OJVRTM
Online Journal of
Veterinary Research©
Volume 19(3): 180-189, 2015.
Hematology,
biochemistry and FNA cytology of primary hepatic plasma cell tumor in a dog:
Zahra
Nikousefat1, Mohammad Hashemnia2*, Moosa Javdani3
Department
of 1Clinical Sciences and 2Pathobiology, School of
Veterinary Medicine, Razi University, Kermanshah,3Department
of Veterinary Surgery and Radiology, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord,
Iran
ABSTRACT
Nikousefat Z, Hashemnia M, Javdani M.,
Hematology, biochemistry and FNA cytology of primary hepatic plasma cell tumor
in a dog, Onl J Vet Res., 19(3): 180-189, 2015. A 7-year-old female Mix breed dog presented with waxing/waning appetite, weight loss and exercise
intolerance. The abdomen felt tight and distended with palpable splenomegaly
with fluid wave. The most remarkable abnormality was a bilirubin concentration of 7.9 mg/dl with globulin and albumin concentrations of 1.9 and 2.1g/dl, respectively. Peritoneal fluid 500ml appeared transparent orange
with
3.0 g/dl total protein. Abdominal
effusion showed 81% non-degenerate neutrophils, 8% small lymphocytes, 10%
macrophages, 1% eosinophils, occasional reactive mesothelial cells and many
erythrocytes. Liver FNA cytology showed highly
cellular smears of numerous hepatocyte aggregates intermingled with many
atypical plasma cells. A diagnosis of a tumor of plasma cell origin was made
based on findings. Primary extramedullary plasmacytoma of the liver is a rare tumor in dogs and should be considered as a differential diagnosis of
hepatic masses.
KEY WORDS: Bichemistry, cytology, dog, plasma
cell, tumor.
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