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OJVRTM

Online Journal of Veterinary Research©

Volume 21(4):178-183, 2017.


Morphopathological and immunohistochemical characteristics of submandibular fibroma in a Horse

 

Khodakaram-Tafti A1, Geramizadeh B2, Zarei-Kordshouli F1, Sadeghpoor A3, Zarei SK4

 

1Department of Pathology, 3Clinical Studies, School of Veterinary Medicine, Shiraz University, 2Pathology, Transplant Research Center, Shiraz University of Medical Sciences, 4Veterinary practitioner, Shiraz, Iran

 

ABSTRACT

 

Khodakaram-Tafti A, Geramizadeh B, Zarei-Kordshouli F, Sadeghpoor A, Zarei SK., Morphopathological and immunohistochemical characteristics of submandibular fibroma in a Horse, Onl J Vet Res., 21(4):178-183, 2017. A 12 year old male Darreh-shouri horse was referred with a slow growing submandibular mass. Grossly, the mass was solitary, well circumscribed, round and of firm consistency. Microscopically, densely packed irregular collagenous connective tissue with many fibrocytes and fibroblasts were observed. There were rare mitotic figures. Adnexal structures were displaced and compressed peripherally. No malignancy and inflammatory reaction was present in the tumoral tissue. Abundant bundles of blue collagen fibers were seen in the tumor sections stained by Masson’s trichrome. In immunohistochemical staining, positive diffuse expression of CD34 was observed. According to the histopathological, histochemical and immunohistochemical findings, the mass was diagnosed as fibroma.

 

Key words: submandibular fibroma, immunohistochemistry, horse.


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