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OJVRTM
Online Journal of Veterinary Research©
Intravenous ketamine-dexmedetomidine
induction-anesthesia in dogs
Narges kavosi;
Hadi Naddaf; Hadi Imani Rastabi; Reza Avizeh
Department
of Clinical Science, Faculty of Veterinary Medicine, Shahid
Chamran University of Ahvaz, Ahvaz, Iran
ABSTRACT
Kavosi
N, Naddaf H, Rastabi HI, Avizeh R., Intravenous ketamine-dexmedetomidine
induction-anaesthesia in dogs, Onl
J Vet Res., 20(6):429-439, 2016. Groups of 6 healthy male mix-breed dogs were given intravenous
2mg/kg Ketamine (KM) with 1ug/kg dexmedetomidine (DX)
(2/1), 1mg/kg KM with 2 µg/kg DX (1/2) or 1mg/kg KM with 1µg/kg DX (1/1).
Anesthesia and cardiorespiratory function were evaluated before and for 60
minutes after induction. Sedation, analgesia, muscle relaxation and recovery
were not different between treatments (p > 0.05). However,
intubation was faster in dogs given 2/1 dose; but head uprising and sternal recumbency, slower (P
< 0.05). Heart
rates decreased significantly in dogs given 1/2 and 1/1 dose at several time points
(P < 0.05). Arterial blood pressure was beyond the
reference range.
Respiratory data did not show any significant differences.
Co-administration of intravenous KM
and DX at different doses could facilitate tracheal intubation and 2/1 doses may
provide optimal cardiovascular respiratory conditions. Subjective scores must
be interpreted with caution.
Key words:
Anesthesia, Dexmedetomidine, Intravenous, Ketamin, dogs.
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