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OJVRTM
Online
Journal of Veterinary Research©
Volume 18(8): 636-645, 2014.
Hematological, hemodynamic, enzyme,
hormonal and acute phase protein changes
in pigs
subjected to open versus laparoscopic adrenalectomy
José Belarmino da Gama Filho DVM PhD1,
Luiz Antônio Franco da Silva DVM PhD2, José Renato Junqueira Borges
DVM PhD3,
Danilo Ferreira RodriguesDVM4, Leonardo
dos Reis Corrêa5, Neusa Margarida Paulo DVM PhD2
1Foundation Jardim Zoológico of Brasília. Brasília, 2School of
Veterinary and Zootechny, Federal University of Goiás, Goiânia, 3Faculdade de
Agronomia e Medicina Veterinária, Universidade de Brasília, 4School of
Veterinary and Zootechny, Federal University of Goiás, Goiânia, 5Veterinary
Center Asa Sul, Brasília, Brazil.
ABSTRACT
Gama Filho JB, Franco da Silva LA, Junqueira Borges JR, Rodrigues DF, Reis Corrêa
L, Margarida Paulo N., Hematological, hemodynamic, enzyme, hormonal and acute
phase protein changes in pigs subjected to open versus laparoscopic
adrenalectomy, Onl J Vet Res., 18(8):
636-645, 2014. Hematological, hemodynamic,
enzyme and hormonal changes during the acute phase response in pigs subjected
to open adrenalectomy or laparoscopy are reported. Groups of 8 pigs each were
subjected to either adrenalectomy by laparotomy or laparoscopy. Two groups were
used as sham laparotomy or laparoscopy controls wherein access to the adrenal
was achieved without adrenalectomy. There were no differences in hematocrit
between any group. Compared with other groups,
leukogram values were elevated in pigs subjected to sham laparotomy. Oxygen saturation, C-reactive protein and
alanine aminotransferase values were lower in pigs subjected to laparoscopic
adrenalectomy. Fifteen days after surgery cortisol levels were lower in pigs
subjected to sham laparotomy. Experimental laparoscopic adrenalectomy in swine
may have lower risk of infection and hemorrhage than conventional adrenalectomy
Key-words: Adrenalectomy, laparoscopy, pigs, acute-phase reaction, hematology,
hemodynamics, enzymes.