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OJVRTM
Online Journal of
Veterinary Research ©
(Including Medical and Laboratory
Research)
Established 1994
ISSN 1328-925X
Volume 27 (10): 566-569, 2023.
Effect of meloxicam
on antibiotic treatment of mastitis in cattle and buffalo
Justin William B, Johnson Rajeswar J.
Department
of Surgery, Madras Veterinary College, Chennai, India.
ABSTRACT
William
JB, Rajeswar JJ., Effect of meloxicam on antibiotic
treatment for mastitis in cattle and buffalo, Onl J
Vet Res., 27 (10): 566-569, 2023. Authors report
clinical efficacy of meloxicam with or without antibiotic for therapy of
mastitis in 20 cattle and buffalo. Ten healthy controls were not treated. One
group of 7 cows and 3 buffalo with clinical mastitis were given 0.5mg/kg
antibiotic intramuscularly, and another 8 cows and 2 buffalo 0.5mg/kg
antibiotic with 0.5mg/kg meloxicam intramuscularly. Surface temperature of injection site was
recorded by thermo sensitive indicator strip before injection, 2 and 24 hours after.
Rectal temperature, heart rate, respiratory rate, hematology, serum proteins
and blood glucose and California mastitis tests were determined at days 1, 2,
3, 7, 15 and 30. Injections did not induce inflammation or temperature.
Compared with cows given only antibiotics,
meloxicam maintained rectal temperatures, respiratory rates ~3% and California mastitis test values 32-45%
lower, whereas hemoglobin ~4%, red cells 5-17% and glucose 5% higher (P <
0.05). Our findings suggest meloxicam boosts effect of antibiotics in cows with
mastitis.
Key
words: Meloxicam – Efficacy – Mastitis.
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