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OJVRTM
Online Journal of Veterinary Research©
Volume 8 : 70-78, 2004. Redacted
2018.
High milk yield in dairy
cows associated with oxidant stress
Löhrke B1, T Viergutz
T 1, Kanitz W1, Göllnitz K1, Becker F1, Hurtienne A2, Schweigert
FJ 2
1FBN
Research Institute for the Biology of Farm Animals Dummerstorf,
2Institute of Nutritional Science, University of Potsdam, Potsdam-Rehbrücke, Germany
ABSTRACT
Löhrke B, Viergutz
T, Kanitz W, Göllnitz K,
Becker F, Hurtienne A, Schweigert
FJ., High milk yield in dairy cows associated with
oxidant stress, Onl J Vet Res., 8 : 70-78, 2004. An imbalance between the formation
and detoxification of oxygen radicals (oxidant stress) may occur during early
lactation known to be associated with an increase in oxidative metabolism to
provide metabolites for the production of milk. However, data from dairy cows
are seemingly lacking. Hydroperoxides (HP) are
indicators for oxidant stress and were measured by the oxidation of Fe2+ in
lipid extracts from low density lipoproteins (LDL) obtained by
ultracentrifugation of serum and precipitation. The Holstein cows examined
(first and second parity, n = 8 and n =5, with a lactation stage of 53 ± 1.4
days postpartum) had HP at levels between 0.1 and 2.1 µM. Positive correlations
were found between HP concentrations and daily milk yield (r = 0.86, P =
0.0004) and milk energy output (r = 0.64, P = 0.04). We conclude that
endogenous oxidation of LDL occurs in dairy cows and increases with higher
productivity.
KEYWORDS: Dairy cow, hydroperoxides,
low density lipoprotein