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OJVRTM
Online Journal of Veterinary Research©
(Including Medical and
Laboratory Research)
Established
1994
ISSN 1328-925X
Volume 26 (10): 722-728, 2022.
Effect of foxtail millet (Setaria italica) on kidney function and serum electrolytes in
sheep and goats
Arash Omidi1, Fateme
Izadi Yazdanabadi2, Ukabed Esmaeilpour3
1Department of Animal Health Management,
Veterinary School, Shiraz University, 2Department of Animal Science, Faculty of
Agriculture, University of Tabriz, 3Department of Animal Science, Faculty of
Agriculture, University of Birjand.
ABSTRACT
Omidi A, Yazdanabadi FI, Esmaeilpour
U., Effect of
foxtail millet (Setaria italica)
on kidney function and serum electrolytes in sheep and goats, Onl J Vet Res., Volume 26 (10): 722-728, 2022. Foxtail
millet may induce hepato-toxic
photosensitization in ruminants. Six goats and sheep
were fed ad libitum alfalfa and tap
water for 7 days and then given foxtail millet 49 days. Jugular blood and body
weight were taken every 7 days for serum blood
urea nitrogen (BUN), creatinine, sodium,
potassium, phosphorus, magnesium and EDTA
blood hematocrit and hemoglobin. The animals were then sacrificed for microscopy of renal tissue. At end of study, 3 lambs
exhibited hepatogenic photosensitization with
erosions and ulcers in head, face, ears, eyelids, hyperemia, yellow sclera and conjunctivis. Clinical and dermal signs in goats were milder
but in 3 we found hyperemia, mild yellow sclera and conjuntivitis.
Both had loose stools from 2nd week. By microscopy of kidney tissue,
we observed moderate to severe congestion with blue-purple sediments in collecting
ducts and mild to severe degeneration of convoluted tubules in sheep but in
goats renal congestion. Compared
with controls, over 7 weeks, serum BUN declined 26-68% but
creatinine increased ~17%, sodium 4-7%, magnesium 33-38%, phosphorus 18-36% , PCV and Hg ~32-36% (P <
0.05). Results suggest that foxtail millet may induce renal toxicity and
grazing should be limited to 1 week.
Keywords: foxtail millet, sheep and goat,
kidney lesions, hepatotoxic photosensitization.