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Online Journal of Veterinary Research©

Volume 18(1):41-46, 2014. Redacted 2017.

Parvoviral induced cerebellar hypoplasia in a kitten

Baharak Akhtardanesh^a DVM DVSc, Bahador Shojaei^b DVM PhD, Reza Kheirandish^cDVM PhD, Nasrin Askari^c DVM.

^aDepartment(s) of Clinical Sciences, ^bBasic Sciences, ^cPathobiology, Faculty of Veterinary Medicine, Shahid Bahonar University of Kerman, Kerman, Iran

ABSTRACT

Akhtardanesh B, Shojaei B, Kheirandish R, Askaric N., Parvoviral induced cerebellar hypoplasia in a kitten, Onl J Vet Res., 18(1):41-46, 2014. Clinical, pathological and diagnostic imaging findings from a 45d old female kitten with cerebellar hypoplasia induced by an intrauterine parvoviral infection are described. Ataxia, dysmetria and intention tremor were present upon examination. Computed tomography revealed radiolucent areas with lower density apparent in both cerebellar hemispheres compared to vermis and brain hemispheres. Congenital panleukopenia was suspected and the animal was euthanized. Post mortem examination revealed prominent cerebellar hypoplasia. Histologically, brain lesions were characterized by segmental loss of the external and internal granular layer with decreased numbers of purkinje cells, a differential diagnosis with primary cerebellar hypoplasia. Amplification of parvovirus DNA confirmed parvoviral induced cerebellar hypoplasia. Preliminary CT scans revealed neurologic disorders in cats.

Key Words: Congenital cerebellar hypoplasia, Cat, CT scan, Panleukopenia

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