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OJVRTM
Online Journal of Veterinary Research©
Volume 16 (3):104-110, 2012. Redacted 2017.
In vitro penetration and survival of Brucella
melitensis in lymphocytic cells of goats.
N. Shaqinah,
M. Mazlina, M. Zamri-Saad,
H. Hazilawati and S. Jasni
Department of Veterinary Pathology and
Microbiology, Faculty of Veterinary Medicine, University Putra Malaysia.
ABSTRACT
N. Shaqinah, M. Mazlina, M. Zamri-Saad, H. Hazilawati and S. Jasni., In vitro penetration and survival of Brucella melitensis in lymphocytic cells of goats, Onl J Vet Res., 16
(3):104-110, 2012. Penetration and survival of B. melitensis in lymphocytic cells of goats was evaluated.
Goats were given formalin-killed B. melitensis subcutaneously and results compared with
unexposed controls. Pasteurella multocida and
Streptococcus agalactiae
bacterial suspensions were used as bacterial controls. Results showed that B. melitensis
penetrated and survived within lymphocytes of both groups. However, goats given
formalin-killed B. melitensis
showed a higher rate of penetration but lower rate of survival when
compared to unexposed controls. Compared with other bacteria, B. melitensis
showed had higher penetration and survival in caprine lymphocytes.
Keywords: Brucella melitensis, rate of penetration, rate of survival,
lymphocytes
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