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OJVRTM
Online Journal of Veterinary Research©
Volume 17(9):460-478, 2013. Extensively Redacted 2017.
Effect of profenofos and carbosulfan on antioxidant enzymes in tissues of the fish Labeo rohita
(Hamilton)
B Nagaraju1,
V Venkata Rathnamma2
1Departments of Biochemistry and 2Zoology,
Acharya Nagarjuna university,
Guntur-522510, A.P, India
ABSTRACT
Nagaraju B, Rathnamma VV., Effect of profenofos
and carbosulfan on antioxidant enzymes in tissues of
the fish Labeo rohita
(Hamilton), Onl J Vet Res., 17(9):460-478, 2013 The effects of lethal and sublethal
concentrations of profenofos an organophosphate
pesticide (OP), and carbosulfan an carbamate
pesticide (CM) on antioxidant enzymes in various vital organs of freshwater
fish Labeo rohita are
described. The fish were exposed for
24h and 8 days to lethal (96h LC50 of 100μg/l,
1.126mg/l) and sublethal concentration (1/10th
96 h LC50 of 10μg/l, 0.1126mg/l) of profenofos
50% and carbosulfan 25%E.C. The results showed
increased catalase, malondialdehyde (MDA), protein
carbonyl, H2O2, and free amino acids in tissues of L.rohita exposed
to profenofos and carbosulfan. L. rohita is
found to be more sensitive to the toxicity of profenofos
compared to carbosulfan. Results suggested that profenofos and carbosulfan
induced production of free radicals and oxidative stress in a dose dependent
manner.
Keywords: concentrations, freshwater, lethal, malondialdehyde,
and toxicity
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