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OJVRTM

Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

Volume 30 (7): 435-441, 2026.

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Amyloidosis and rupture of liver in cat with bowel disease.

Abbaszade M, Selk Ghaffari M, Dezfoulian O, Aledavood SJ, Jahanzad I.

Faculty (s) Veterinary Medicine, University of Tehran., Islamic Azad University-Karaj Branch. University of Lorastan, Khorramabad, University of Medical Sciences of Tehran, Iran

ABSTRACT

Abbaszade M, Selk Ghaffari M, Dezfoulian O, Aledavood SJ and Jahanzad I. Amyloidosis and rupture of liver in cat with bowel disease. Onl J Vet Res, 30 (7): 427-434, 2026. A 7-year-old cross-bred cat treated with metronidazole for chronic diarrhea, died 10 days later. Onset of signs were frequent diarrhea, vomiting and weight loss. At necropsy abdominal cavity was filled with bloody fluid and clots. By microscopy, in liver we observed pink-reddish parenchyma of liver and sinusoids. In small intestine we found lamina propria of small intestine infiltrated by large mononuclear inflammatory cells of lymphocytes and plasma cells. By immunohistochemistry we observed Amyloid A in hepatocytes and spaces of disse in liver and cytoplasm of renal tubules negative for both kappa and lambda chain antibodies.

Key words: hepatic rupture, amyloidosis, inflammatory bowel disease, cat

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