Volume 23 (4):315-320, 2019.
Nematode resistance to ivermectin,
levamisole and fenbendazole in sheep flocks
determined
by fecal egg count reduction test.*
A Varadharajan, R Gnansekar
and S Kothandaraman.
Division of Animal Husbandry, Faculty of
Agriculture, Annamalai University, Annamalai Nagar – 608 002. Tamil
Nadu, India. *Part of PhD
research work submitted by the First Author.
ABSTRACT
Varadharajan
A, Gnansekar R, Kothandaraman
S., Nematode resistance to ivermectin, levamisole and
fenbendazole in sheep flocks evaluated by fecal egg
count reduction test, Onl J Vet Res., 23 (4):315-320,
2019. Resistance of
gastrointestinal nematodes to ivermectin, levamisole,
and fenbendazole treatments in 6 flocks of eighty,
5-15 month old male-female sheep in Cuddalore
district, Tamil Nadu, India, was assessed by fecal egg count reduction tests
(FECR). The sheep had not been treated with anthelmintics
2 months before and became infested by grazing on pasture. Faecal
egg counts were done on day 0 before treatments and 10 days after. Before
treatment, sheep were fasted 8h and then gavaged
5mg/kg fenbendazole or 15mg/kg levamisole
Hydrochloride or injected subcutaneous 0.1mg ivermectin.
Controls (n=20) were not treated. Ten gram feces were taken at day 0 before
treatment and 10 days after for tube flotation nematode egg count. Resistance
was determined according to WAAVP as < 95 % and fecal culture was done to
identify nematode species. We found high levels of anthelmintic resistance to fenbendazole (50-89%) moderate to levamisole (93-95%) and
low to ivermectin (94-97%). H. contortus
was most frequent resistant nematode. We found high levels of resistance to fenbendazole in all flocks probably due to frequent routine
use.
Key Words: Anthelmintic resistance, Sheep, ivermectin,
levamisole, fenbendazole, Cuddalore,
India.
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