©1996-2021. All Rights Reserved. Online
Journal of Veterinary Research. You may not store these pages in any
form except for your own personal use. All other usage or distribution is
illegal under international copyright treaties. Permission to
use any of these pages in any other way besides the before mentioned must be
gained in writing from the publisher. This article is exclusively
copyrighted in its entirety to OJVR. This article may be copied once but may
not be, reproduced or re-transmitted without the express permission of the
editors. This journal satisfies the refereeing requirements (DEST) for the
Higher Education Research Data Collection (Australia). Linking: To link to this
page or any pages linking to this page you must link directly to this page only
here rather than put up your own page.
OJVRTM
Online Journal of Veterinary Research©
Volume 23 (12):1195-1211,
2019.
Effect of silver nanoparticle supplement on mycotoxicity
in Ross 308 broilers.
Jawad BJ and ALwan MJ.
Department of Veterinary Pathology, College of Veterinary Medicine,
University of Baghdad, Iraq.
ABSTRACT
Jawad BJ, Alwan MJ., Effect of silver
nanoparticle supplement on mycotoxicity in Ross 308
broilers, Onl J Vet Res., Onl J Vet Res., 23
(12):1195-1211, 2019. We evaluated
effect of silver nanoparticle supplement on mycotoxicity
markers in Ross broilers. Three groups of 5 seven day old chicks each were fed
basal diet daily for 7 weeks mycotoxin AFB1= 10 ppb, Ochratoxin =1.4 ppb, T-2=129.9 ppb (Group 1), mycotoxins with 5 mg/Kg silver
nanoparticles (2) or corn - soybean basal diet (Controls). Thirty days after treatment, blood was taken for TNF-α,
IL 10, phagocytosis tests and glutathione peroxidase. Chicks were weighed every
7 days, then sacrificed at 7 weeks for bursal, spleen
weight and histopathology. Compared with chicks given mycotoxin feed, body
weights in those supplemented nanoparticles were 11-22% greater and 21-40% in basal
diet controls (21-40%) (P < 0.05). At 30 days, serum TNF-α
was 43% higher in those given nanoparticle supplement and 33% in controls (P
< 0.05) but we found no differences in TLF-1. However, in those given
nanoparticles serum gluthatione was 82% lower and in
controls 56% lower. Bursae were 68% heavier with nanoparticles and 59% controls
but Spleen weights 34 and 18% lower, respectively. We observed severe hemorrhage, necrosis, apoptosis, suppurative inflammation and mononuclear cell infiltration as well as depletion of
lymphoid tissue in birds feed fed contaminated with mycotoxin but found milder
lesions in those given nanoparticles.
Keywords: Mycotoxins, Silver Nanoparticles, Broiler
Chicken, Glutathione Peroxidase. Raw data provided.
FULL-TEXT (SUBSCRIBE OR PURCHASE TITLE)