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OJVRTM

Online Journal of Veterinary Research©

Volume 20(12):761-767, 2016.

Effect of hydroalcoholic extract of Scrophularia striata on Escherichia coli O157:H7 (ATCC No. 25922)

 

Mohammad Mahdi Zangeneh1,3, Reza Tahvilian2, Fariba Najafi3, Lida  Haghnazari4, Akram Zangeneh3,5*

 

1Department of Clinical Sciences, Faculty of Veterinary Medicine, Razi University, 2Research pharmaceutical center, School of Pharmacy, Kermanshah University of Medical Sciences, 3Dermatology, 4Biochemistry, School of Medicine, Kermanshah University of Medical Science, 5Microbiology, Pathobiology & Basic sciences, Veterinary Faculty, Razi University, Kermanshah, Iran.

ABSTRACT

 

 

Zangeneh MM, TahvilianR, Najafi F, Haghnazari L, Zangeneh A., Effect of hydroalcoholic extract of Scrophularia striata on Escherichia coli O157:H7 (ATCC No. 25922), Onl J Vet Res.,  20(12):761-767, 2016. Scrophularia striata (SS) has been used as an antioxidant, antiparasitic, antifungal, antiviral, and antiflammatory agent. Minimum inhibitory concentration (MIC) of SS hydroalcoholic extract on growth of Escherichia coli O157:H7 (EC) (ATCC No. 25922) on agar disk, well diffusion and macrobroth tube test was ~0.031 g/ml. There were discrepancies in sensitivity to SS: In agar disk diffusion there was no inhibitory effect at 0.007 g/ml and in agar well diffusion test, no inhibitory effect at 0.007 or 0.015 g/ml. 

 

Keywords: Scrophularia striata; Hydroalcoholic extract; Antibacterial activities, Macro-dilution method, Agar disk diffusion method, Agar well diffusion method. 

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