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OJVRTM

Online Journal of Veterinary Research©

 

Volume 18(10): 823-829, 2014. Redacted 2018.


 Effect of alcoholic extract of Tarantula cubensis on wound healing in dogs

 

Mahdieh Rezaei1 DVSc, Behrooz Fathi2 PhD, Kamran Sardari3 DVSc.

 

1Department(s) of Clinical Science, Faculty of Veterinary Medicine, Shahid Bahonar University, Kerman, 2Basic Sciences, 3Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

 

ABSTRACT

 

Rezaei M, Fathi B, Sardari K., Effect of alcoholic extract of Tarantula cubensis on wound healing in dogs, Onl J Vet Res., 18(10): 823-829,  2014.  We report effects of alcoholic extract of whole tarantula cubensis (Theranekron®), on healing of skin wounds in 5 dogs. Under general anesthesia, symmetrical control and treated skin wounds (20×20 mm) were created on the dorsum of each dog. Wounds were treated with 0.4ml tarantula extract subcutaneously (SC) and 0.4ml normal saline (control wound). Healing was monitored by digital images of wounds taken at 0, 3, 6, 12, 15, 18 and 21 days. Areas of epithelialization and granulation tissue were measured using Scion Image software allowing percentages of wound contraction, epithelialization and healing to be calculated. Epithelialization occurred by day 3 on treated wounds and at day 5 in control wounds.  We found no significant differences in percentage of wound contraction and epithelialization between test and control wounds up to day 9 but by day 12 and 15 improved healing values may have occurred in treated wounds.

 

Keywords: Theranekron, Tarantula cubensis, Epithelialization, Wound contraction, Wound healing, Dog.


 

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