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OJVRTM
Online Journal of Veterinary Research©
(Including
Medical and Laboratory Research)
Established
1994
ISSN
1328-925X
Volume 28(3): 156-162, 2024.
Effect of Triganella foenum graecum gavage on
sperm and serum thyroid hormones
in
hypothyroid and normal Albino mice.
Fouad Ziedan Hamza Al-Quraishi, Bassam Abdulameer
Mohammed A-Madany, Mohammed Abdaljaleel
Fadhel Al-Kraawi, Nadia K.
J. Al-Dawah
Department of Physiology, Pharmacology and Chemistry, College of Veterinary
Medicine, University of Kufa, Kufa,
Iraq.
ABSTRACT
Hamza
Al-Quraishi FZ, Mohammed A-Madany
BA, Fadhel Al-Kraawi MA,
Al-Dawah NKF., Effect of Triganella
foenum graecum gavage on
sperm and serum thyroid hormones in hypothyroid and normal albino mice, Onl J Vet Res., 28(3):
156-162, 2024. We report effect of Triganella foenum graecum (Fenugreek) and thyroxin in normal and
hypothyroid albino mice on sperm and serum thyroid stimulating, thyroxine and
triiodothyronine hormones. Mice were gavaged 15mg/kg fenugeek or injected 0.1mg/kg thyroxin introperitoneally
daily for 30 days. Normal and hypothyroid controls were gavaged? Saline. We determined serum hormones by
ELISA and RIA kits and semen motility, progressive motility, viability and
morphology from epidimal samples. Compared with
normal controls, hypothyroid controls were associated with enhanced serum TSH
(~65%) and
reduced T3 and T4 (-62-73%) (P < 0.05) whereas hypothyroid
mice given thyroxin with or without feenugeek had
reduced TSH but maintained normal serum T3 and T4 levels. Hypothyroid
mice had reduced sperm count, motility and viability whereas trhyroxin and fenugreek was associated with increased
values.
Key
words: Hypothyroidism, Sperm, Thyroxine, Fenugreek, Mice.
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