©2021-2032 All Rights Reserved. Online
Journal of Veterinary Research . You may not store these pages in any
form except for your own personal use. All other usage or distribution is
illegal under international copyright treaties. Permission to use any of these
pages in any other way besides the before mentioned
must be gained in writing from the publisher. This article is exclusively
copyrighted in its entirety to OJB publications. This article may be copied
once but may not be, reproduced or re-transmitted
without the express permission of the editors. This journal
satisfies the refereeing requirements (DEST) for the Higher Education Research
Data Collection (Australia). Linking:To link to this page or any pages linking to
this page you must link directly to this page only here rather than put up your
own page.
OJVRTM
Online
Journal of Veterinary Research©
Epidemiological assessment of vaccine
efficacy
GV Asokan, A Padmaraj
and Johnsi Koruth.
Institute
of veterinary preventive medicine, Ranipet, Tamil
nadu-632 402 India
ABSTRACT
Asokan GV, Padmaraj
A, Koruth J., Epidemiological
assessment of vaccine efficacy, Onl J Vet Res., 25
(5): 341-350, 2021. Success of epidemiological programs
against infectious diseases depends on effective prophylactic vaccines.
Although efficacy and effectiveness are used interchangeably, effectiveness
depends upon efficacy. Few methods are
in use to assess the efficacy of the vaccine, a randomized double blind
controlled trial is the least ambiguous method for evaluation. Observational
designs for vaccine efficacy include cohort and case control and are useful
when comparing vaccines with very large effectiveness. Modeling helps in
designing vaccine. Serologic responses to antigens in combination vaccine
differ from those obtained with separate administration of the components.
Creation of a vaccine advisory and control authority is imminent.
Key words : Epidemiology,
Vaccines, efficacy, effectiveness.