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OJVRTM

 Online Journal of Veterinary Research©

 

Volume 18(1):35-40, 2014. Redacted 2017.


In vitro antibacterial activity of hornet venom from Vespa orientalis.

 

Jalaei J (MS), Fazeli M (DVM, PhD), Rajaian H(DVM, PhD), Shomali T (DVM, PhD)

 

1Division of Pharmacology and Toxicology, Department of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

 

ABSTRACT

 

Jalaei J, Fazeli M, Rajaian H, Shomali T., In vitro antibacterial activity of hornet venom from Vespa orientalis., Onl J Vet Res., 18(1):35-40, 2014. Minimum Inhibitory Concentrations (MIC) values for venom sac extract from Vespa orientalis venom (Vo) against Staphylococcus intermedius, Bacillus cereus, Pseudomonas aeruginosa and Salmonella typhimurium determined by microtiter broth dilution are reported. Inhibition zones were measured by disk diffusion with a positive tetracycline control. The growth curve of control bacteria was compared with bacteria grown in broth for 24 hr with Vo twice the MIC value and 16 µg/ml tetracycline. Results suggested that P. aeruginosa and S. typhimurium were most resistant and sensitive to Vo with some activity against S. Intermedius and B cereus. The antimicrobial activity of Vo against bacteria was concentration-dependent as demonstrated by growth curves, but its MIC value was much higher than that of tetracycline.

 

Key words: Vespa orientalis venom; antibacterial effect; in vitro.


 

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