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OJVRTM
Online Journal of Veterinary Research©
Volume 18(11): 859-868, 2014, redacted 2018.
Effects of Origanum vulgare on epididymal sperm in mice after chronic copper
sulfate administration.
Jalil Abshenas1* , Ehsanollah Sakhaee1, Ali Mostafavi3
1Department of Clinical Sciences, 1,2School of Veterinary
Medicine, Shahid Bahonar
University of Kerman, Kerman, Iran.
ABSTRACT
Abshenas J, Sakhaee E, Mostafavi
A., Effects of Origanum vulgare on epididymal sperm in mice after chronic copper sulfate
administration, Onl J Vet Res., 18(11): 859-868, 2014.
Effects of O. vulgare extract on epididymal sperm quality following experimentally induced
copper poisoning in mice are described. Groups of 12 mice each were gavaged copper
sulfate (CS) 200mg/day in 0.2ml, O. vulgare 400mg/day in drinking water or O.
vulgare with CS for 6 weeks. Controls were gavaged
0.2ml/day distilled water also for 6 weeks. Administration of CS caused a
significant decrease in sperm count, viability and motility after 42 days
compared with controls. Sperm count recovered in mice gavaged
CS with O. vulgare 42 days compared with CS mice There also was an improvement in sperm viability
and motility (p<0.001). The findings suggest that O vulgare may protect against chronic CS toxicity.
Keywords:
Copper poisoning. Origanum vulgare. Sperm quality. Mice.
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