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OJVRTM

Online Journal of Veterinary Research©

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume  29 (10): 639-649, 2025.


Yersinia as antibodies for diagnosis of Brucellosis in cattle.

 

Nagaraju NR, Isloor S, Sathyanarayana Rao M, Rajasekhar M.

 

Department of Veterinary Public Health Veterinary college, University of Agricultural Sciences,  Project Directorate on Animal Disease, Monitoring and Surveillance Project  Indian Council of Agricultural Research, Hebbal, Bangalore, India.

 

SUMMARY

 

Nagaraju NR, S. Isloor, M.Sathyanarayana Rao, M. Rajasekhar M.,  Yersinia as antibodies for diagnosis of Brucellosis in cattle,,  Onl J Vet Res., 29 (10): 639-649, 2025.  A serological survey of bovine yersiniosis was performed in India to determine if Y. enterocolitica serotype O:9 is responsible for false positive reactions in the diagnosis of brucellosis.   A total of 1521 bovine sera were tested. Of these, 505 were positive and 1016 negative to Brucella spp with avidin-biotin ELISA.   A total of 108 were positive for Yersinia antibodies (7.1% incidence) of which 43 were positive for both yersiniosis and brucellosis, and 65 were positive for yersiniosis with antibodies against Y.enterocolitica other than serotype O:9.  The Yersinia test did not identify false positive brucellosis reactions; for Y.enterocolitica O:9 (or other Yersinia species) and B.abortus, only a Brucella test will diagnose the disease. Monoclonal antibody ELISA, Lymphocyte transformation or Interferon-gamma assay may be more specific for Brucella spp. The results suggest a low incidence of  Y.enterocolitica O:9 in Indian cattle.

 

KEY WORDS:  Brucella abortus - Bovines – Cross-reaction - ELISA - India - Serodiagnosis - Yersinia enterocolitica- Yersinia outer membrane proteins.


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