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OJVR
Online
Journal
of Veterinary Research©
Volume
14 (1):66-74,
2010
Effect
of symbiotic yogurt on blood biochemical parameters in streptozotocin-Induced diabetic rats
Seyed Mohammad
Mazloomi1,*, Seyed Shahram
Shekarforoush2, Javad Sajedianfard3
1DVM,
2DVM,
PhD, Department of Food Hygiene and Public Health, School of Veterinary
Medicine,
3DVM,
PhD, Department of Basic Sciences, School of
Veterinary Medicine, Shiraz University, Iran.
ABSTRACT
Mazloomi SM, Shekarforoush S, Sajedianfard
J., Effect of Symbiotic Yogurt on Blood
Biochemical Parameters in Streptozotocin-Induced
Diabetic
Rats, Online J Vet Res, 14
(1):66-74, 2010. In this
study, the effect of synbiotic yogurt
containing Lactobacillus
acidophilus LA-5 and inulin (20 mL per day for each rat) on blood biochemical
parameters
were studied in streptozotocin-induced
diabetic rats for
60 days. Synbiotic
and probiotic milk products reduced the
level of glycosylated hemoglobin, total and low density
lipoprotein cholesterol.
They also diminished the reduction of high density lipoprotein
cholesterol and
insulin level in diabetic rats (p<0.05). Only synbiotic
yogurt significantly (p<0.05) decreased serum triglycerides. Probiotic and synbiotic
milk
products arrested the elevation of alanine
amino transferase, aspartate
amino transferase and
blood urea nitrogen levels of
diabetic rats
(p<0.05). Results showed that supplementation probiotic
yogurt containing L. acidophilus LA-5 with inulin
increased
the efficacy of probiotic yogurt to
suppress diabetes
by more inhibition of dyslipidemia.
Keywords: Synbiotic, Yogurt, Lactobacillus,
Inulin, Diabetes, Rats.