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OJVRTM
Online Journal of Veterinary Research©
Volume 21(2):77-80, 2017.
Effect of Cinnamomum zelanicumon oil on hyponeophagia
anxiety test in Balb C male mice.
Elahe Faramarzi1, Mohammad Mahdi Zangeneh2*,
Akram Zangeneh3, Rohalah
Moradi4
Department(s) of 1Mineral Chemistry, Faculty of Chemistry, 2Clinical
Sciences, Faculty of Veterinary Medicine, 3Microbiology,
Pathobiology & Basic Sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, 4Chemistry, Payame Noor University, Tehran, Iran.
ABSTRACT
Faramarzi E, Zangeneh
MM, Zangeneh A, Moradi R., Effect
of Cinnamomum zelanicumon
oil on hyponeophagia anxiety test in Balb C male mice Onl J Vet Res., 21(2):77-80, 2017. Authors describe effect of essential oil of C. zelanicum
on anxiety markers in male C balb mice using the hyponeophagia test. Groups of 6 mice each were given 200,
400 or 600 mg/kg essential oil of C. verum per os. Another 6 mice were used as saline controls. A hyponeophagia unit with a food spout allowed mice to feed
and roam freely during 120 seconds at day 15, 20 and 25 after treatments. Time
spent feeding and number of stools were determined.
After each trial the recipient was cleaned with ethanol to inhibit a bias based
on olfactory cues. Results suggest that compared with controls, mice given C. verum fed
sooner and defecated less.
Keywords: Cinnamomum verum, anxiolytic properties, Hyponeophagia test.